Serena Williams is a global icon and one of the most dominant athletes in tennis history. Over her career, she won 23 Grand Slam singles titles, more than any other player in the Open Era. Her powerful serve, fierce mentality, and longevity helped her remain at the top of the sport for more than two decades. She won her first major in 1999 and her most recent in 2017, a span of 18 years. Serena came just one major short of tying the all-time Grand Slam singles title record held by Margaret Court. So while Serena reigns supreme in the Open Era, she’s not the all-time record holder for most Grand Slam titles.